pyrimidin-5-ylboronic acid
5-Pyrimidinylboronic acid
CAS: 109299-78-7
Molecular Formula: C4H5BN2O2
pyrimidin-5-ylboronic acid - Names and Identifiers
pyrimidin-5-ylboronic acid - Physico-chemical Properties
| Molecular Formula | C4H5BN2O2 |
| Molar Mass | 123.91 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Melting Point | 110-114 °C |
| Boling Point | 334.7±34.0 °C(Predicted) |
| Flash Point | 156.2°C |
| Solubility | Soluble in Ether, MeOH, DMSO, THF. |
| Vapor Presure | 4.95E-05mmHg at 25°C |
| Appearance | White powder |
| Color | White to Orange to Green |
| pKa | 5.23±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.534 |
| MDL | MFCD03002366 |
pyrimidin-5-ylboronic acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
pyrimidin-5-ylboronic acid - Introduction
5-Pyrimidine boronic acid is an organic compound with the chemical formula C4H4BNO3. The following is a description of the properties, uses, preparation methods and safety information of 5-pyrimidine boronic acid:
Nature:
-Appearance: 5-pyrimidine boronic acid is a white crystalline solid.
-Solubility: less soluble in water, soluble in polar organic solvents such as alcohol, ether, etc.
-Chemical properties: 5-pyrimidine boronic acid is a weak acid that can react with alkali to form the corresponding salt.
Use:
-5-pyrimidine boronic acid is commonly used as a catalyst in organic synthesis. Among them, its etherifying agent salt can catalyze the esterification reaction of alcohol and ether.
-It can also be used as a raw material in organic synthesis, such as a precursor for the synthesis of other organic compounds.
-It is also used in the preparation of some fluorescent materials and fluorescent dyes.
Preparation Method:
The preparation of -5-pyrimidine boronic acid is usually obtained by reacting 5-pyrimidine with boric acid. For example, 5-pyrimidine is dissolved in an organic solvent, boric acid is added, and the reaction is heated, and after a period of time under appropriate conditions, a white crystalline 5-pyrimidine boronic acid is obtained.
Safety Information:
-5-pyrimidine boric acid is relatively stable, and there is no obvious safety risk during normal use.
-but still need to pay attention to protective measures, avoid contact with skin and eyes. Wear appropriate personal protective equipment such as lab gloves, goggles, etc.
-Waste disposal shall be carried out in a safe and environmentally friendly manner in accordance with local regulations.
Nature:
-Appearance: 5-pyrimidine boronic acid is a white crystalline solid.
-Solubility: less soluble in water, soluble in polar organic solvents such as alcohol, ether, etc.
-Chemical properties: 5-pyrimidine boronic acid is a weak acid that can react with alkali to form the corresponding salt.
Use:
-5-pyrimidine boronic acid is commonly used as a catalyst in organic synthesis. Among them, its etherifying agent salt can catalyze the esterification reaction of alcohol and ether.
-It can also be used as a raw material in organic synthesis, such as a precursor for the synthesis of other organic compounds.
-It is also used in the preparation of some fluorescent materials and fluorescent dyes.
Preparation Method:
The preparation of -5-pyrimidine boronic acid is usually obtained by reacting 5-pyrimidine with boric acid. For example, 5-pyrimidine is dissolved in an organic solvent, boric acid is added, and the reaction is heated, and after a period of time under appropriate conditions, a white crystalline 5-pyrimidine boronic acid is obtained.
Safety Information:
-5-pyrimidine boric acid is relatively stable, and there is no obvious safety risk during normal use.
-but still need to pay attention to protective measures, avoid contact with skin and eyes. Wear appropriate personal protective equipment such as lab gloves, goggles, etc.
-Waste disposal shall be carried out in a safe and environmentally friendly manner in accordance with local regulations.
Last Update：2024-04-10 22:29:15
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CAS: 109299-78-7
Tel: 18301782025
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QQ: 3008007409
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CAS: 109299-78-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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